Stevens-Johnson syndrome

Sudden illness and injury. Also called: SJS.

How common is Stevens-Johnson syndrome in the US?

Hospitalizations involving Stevens-Johnson syndrome (SJS), SJS-TEN overlap syndrome, or toxic epidermal necrolysis (TEN), identified by ICD-9/ICD-10 codes: 51,040 (SJS/TEN hospitalizations, United States, National Inpatient Sample, 2010-2020 (count over 11 years, not an annual rate); United States (National Inpatient Sample, nationally representative hospital sample), 2010-2020). Source: JAAD international, 2023. Label: REPORTED.

• 51,040 Hospitalizations involving Stevens-Johnson syndrome (SJS), SJS-TEN overlap syndrome, or toxic epidermal necrolysis (TEN), identified by ICD-9/ICD-10 codes. Out of: SJS/TEN hospitalizations, United States, National Inpatient Sample, 2010-2020 (count over 11 years, not an annual rate). Where: United States (National Inpatient Sample, nationally representative hospital sample). When: 2010-2020. Hospitalized cases only, and combines SJS, SJS-TEN overlap, and TEN together; not all SJS cases and not an annualized figure. Label: REPORTED.

  We identified 51,040 hospitalizations involving SJS/TEN.

  Source: Epidemiology of Stevens-Johnson syndrome and toxic epidermal necrolysis in the United States and factors predictive of outcome. JAAD international, 2023. PubMed 37575514. DOI 10.1016/j.jdin.2023.06.014.

Each figure measures something different. Do not compare them with each other or with other conditions.

Medical codes

• ICD-10-CM FY2026: L51.1 Stevens-Johnson syndrome (exact)

Research activity

As of 2026-09-24: 41 registered studies on ClinicalTrials.gov (search Stevens-Johnson Syndrome) and 1,441 PubMed records, 2021 to 2025. A count of records is not how common or serious the condition is.

Population information, not medical advice. Methodology · Known limitations