Heart attack (acute myocardial infarction)

Sudden illness and injury. Also called: Acute myocardial infarction, AMI.

How common is Heart attack (acute myocardial infarction) in the US?

Adult hospitalizations with acute myocardial infarction (AMI), excluding type 2 MI, inter-hospital transfers, and palliative care encounters: 6,215,139 (AMI hospitalizations, United States, National Inpatient Sample, 2016-2023 (weighted count over 8 years, not an annual rate); United States (National Inpatient Sample, nationally representative hospital sample), 2016-2023). Source: General hospital psychiatry, 2026. Label: REPORTED.

• 6,215,139 Adult hospitalizations with acute myocardial infarction (AMI), excluding type 2 MI, inter-hospital transfers, and palliative care encounters. Out of: AMI hospitalizations, United States, National Inpatient Sample, 2016-2023 (weighted count over 8 years, not an annual rate). Where: United States (National Inpatient Sample, nationally representative hospital sample). When: 2016-2023. Hospitalized cases only, excludes type 2 MI, inter-hospital transfers, and palliative care encounters; not all AMI cases (e.g. those who died before reaching hospital). Label: REPORTED.

  Among 6,215,139 weighted AMI hospitalizations, 125,905 (2.0%) involved patients with SMI.

  Source: Differential disparities in coronary revascularization across serious mental illness subtypes: A Nationwide analysis of 6.2 million myocardial infarction hospitalizations. General hospital psychiatry, 2026. PubMed 42143918. DOI 10.1016/j.genhosppsych.2026.05.014.

Each figure measures something different. Do not compare them with each other or with other conditions.

Medical codes

• ICD-10-CM FY2026: I21.9 Acute myocardial infarction, unspecified (narrower). Other codes in this category also apply.

Research activity

As of 2026-09-24: 1,863 registered studies on ClinicalTrials.gov (search Acute Myocardial Infarction) and 13,327 PubMed records, 2021 to 2025. A count of records is not how common or serious the condition is.

Population information, not medical advice. Methodology · Known limitations