Wilson Disease
Wilson Disease is indexed under Rare / Orphan Chronic, Copper Metabolism. Also known as hepatolenticular degeneration.
- US prevalence
- Older studies estimated Wilson disease at about 1 in 30,000 people; newer genetic studies suggest pathogenic variants may be more common than diagnosed disease Source: NIH/NIDDK, Definition & Facts for Wilson Disease. Federal source. Label: VERIFIED.
- ICD-10-CM codes
- E83.01
- Typical onset
- Typically 5-35 years; hepatic presentation earlier, neurologic later
- Course
- lifelong
- Body systems
- hepatic, neurological
- Sex differences
- Equal (autosomal recessive)
- Racial and ethnic differences
- Pan-ethnic; higher in populations with more consanguinity
What this page does not establish
These figures describe populations, not individuals, and none of them is a diagnosis or a treatment recommendation. Prevalence estimates are approximate and reflect published ranges. Disparity figures are reported patterns, not causes.
Taxonomy last reviewed 2026-05-19. Each figure on the interactive page carries its own source and retrieval date, which can be later than this review.
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