Advanced Systemic Mastocytosis

Advanced Systemic Mastocytosis is indexed under Rare / Orphan Chronic, Mast Cell Disorders. Also known as AdvSM, aggressive SM, mast cell leukemia.

US prevalence

~10-20% of systemic mastocytosis cases Source: ASH. This figure comes from a professional society, registry, or study rather than a federal source. Label: REPORTED.

ICD-10-CM codes

D47.02

Typical onset

40-60 years

Course

progressive

Body systems

hematologic, hepatic, gastrointestinal

Sex differences

M:F ~1:1

Racial and ethnic differences

Limited data

What this page does not establish

These figures describe populations, not individuals, and none of them is a diagnosis or a treatment recommendation. Prevalence estimates are approximate and reflect published ranges. Disparity figures are reported patterns, not causes.

Taxonomy last reviewed 2026-05-19. Each figure on the interactive page carries its own source and retrieval date, which can be later than this review.

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