Systemic Lupus Erythematosus

Systemic Lupus Erythematosus is indexed under Musculoskeletal & Connective Tissue, Systemic Autoimmune. Also known as SLE, lupus.

US prevalence

~204,000 people in the United States are estimated to have systemic lupus erythematosus Source: CDC — People with Lupus. Federal source. Label: VERIFIED.

ICD-10-CM codes

M32, M32.9

Typical onset

15-44 years; peak 20s-30s

Course

episodic

Body systems

musculoskeletal, renal, dermatologic, cardiovascular, neurological

Sex differences

F:M ~9:1

Racial and ethnic differences

2-3x more common in Black, Hispanic, Asian, and AIAN women; Black women have most severe disease

What this page does not establish

These figures describe populations, not individuals, and none of them is a diagnosis or a treatment recommendation. Prevalence estimates are approximate and reflect published ranges. Disparity figures are reported patterns, not causes.

Taxonomy last reviewed 2026-05-19. Each figure on the interactive page carries its own source and retrieval date, which can be later than this review.

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