Substance Use Disorders

Substance Use Disorders is indexed under Mental Health & Behavioral, Substance-Related. Also known as SUD, addiction, alcohol use disorder, opioid use disorder.

US prevalence

~44.6 million people age 12 or older (15.3%) had a past-year substance use disorder in 2025; alcohol use disorder 25.7 million; opioid use disorder 4.0 million Source: SAMHSA, National Survey on Drug Use and Health, 2025 NSDUH Annual National Report, published July 27, 2026. Federal source. Label: VERIFIED.

ICD-10-CM codes

F10, F11, F12, F13, F14, F15, F19

Typical onset

Peak onset 18-25; varies by substance

Course

managed

Body systems

psychiatric, neurological, hepatic

Sex differences

M:F ~2:1 overall; gap narrowing for alcohol and some drugs

Racial and ethnic differences

American Indian/Alaska Native highest rates; complex socioeconomic determinants across groups

What this page does not establish

These figures describe populations, not individuals, and none of them is a diagnosis or a treatment recommendation. Prevalence estimates are approximate and reflect published ranges. Disparity figures are reported patterns, not causes.

Taxonomy last reviewed 2026-05-19. Each figure on the interactive page carries its own source and retrieval date, which can be later than this review.

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