Sickle Cell Disease
Sickle Cell Disease is indexed under Hematologic, Hemoglobinopathies. Also known as SCD, sickle cell anemia, HbSS.
- US prevalence
- ~100,000 people in the United States; the exact number is unknown Source: CDC — Data and Statistics on Sickle Cell Disease. Federal source. Label: VERIFIED.
- ICD-10-CM codes
- D57, D57.1
- Typical onset
- Diagnosed at birth via newborn screening; lifelong
- Course
- lifelong
- Body systems
- hematologic, cardiovascular, pulmonary, renal, neurological
- Sex differences
- Equal (autosomal recessive)
- Racial and ethnic differences
- Primarily affects Black Americans (~1 in 365); also Hispanic, Mediterranean, Middle Eastern, South Asian
What this page does not establish
These figures describe populations, not individuals, and none of them is a diagnosis or a treatment recommendation. Prevalence estimates are approximate and reflect published ranges. Disparity figures are reported patterns, not causes.
Taxonomy last reviewed 2026-05-19. Each figure on the interactive page carries its own source and retrieval date, which can be later than this review.
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