Primary Immunodeficiency Diseases (Other)
Primary Immunodeficiency Diseases (Other) is indexed under Autoimmune & Inflammatory, Primary Immunodeficiency. Also known as PID, inborn errors of immunity.
- US prevalence
- ~500,000 (many undiagnosed); >450 identified genetic defects Source: IDF; JMF. This figure comes from a professional society, registry, or study rather than a federal source. Label: REPORTED.
- ICD-10-CM codes
- D80, D81, D82, D84
- Typical onset
- Childhood for severe forms; milder forms diagnosed at any age
- Course
- lifelong
- Body systems
- immunologic
- Sex differences
- X-linked forms affect males predominantly
- Racial and ethnic differences
- Varies by specific disorder; SCID screening improving equity
What this page does not establish
These figures describe populations, not individuals, and none of them is a diagnosis or a treatment recommendation. Prevalence estimates are approximate and reflect published ranges. Disparity figures are reported patterns, not causes.
Taxonomy last reviewed 2026-05-19. Each figure on the interactive page carries its own source and retrieval date, which can be later than this review.
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