Premature Ovarian Insufficiency
Premature Ovarian Insufficiency is indexed under Reproductive & Pelvic, Endocrine Reproductive. Also known as POI, premature ovarian failure, early menopause.
- US prevalence
- ~1% of women <40; ~0.1% <30 Source: ASRM; NIH NICHD. Cites federal and non-federal sources, and the record does not say which one gave this figure. Label: REPORTED.
- ICD-10-CM codes
- E28.31
- Typical onset
- Before age 40 by definition
- Course
- lifelong
- Body systems
- endocrine, reproductive
- Sex differences
- Exclusively female
- Racial and ethnic differences
- May be more common in Black and Hispanic women
What this page does not establish
These figures describe populations, not individuals, and none of them is a diagnosis or a treatment recommendation. Prevalence estimates are approximate and reflect published ranges. Disparity figures are reported patterns, not causes.
Taxonomy last reviewed 2026-05-19. Each figure on the interactive page carries its own source and retrieval date, which can be later than this review.
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