Porphyria

Porphyria is indexed under Rare / Orphan Chronic, Heme Synthesis Disorders. Also known as acute intermittent porphyria, AIP, porphyria cutanea tarda, PCT.

US prevalence

AIP: ~1 in 10,000-20,000 carriers; PCT: most common; ~5-10 per 100,000 Source: APF; NIH. Cites federal and non-federal sources, and the record does not say which one gave this figure. Label: REPORTED.

ICD-10-CM codes

E80.2, E80.0, E80.1

Typical onset

AIP: 20-40; PCT: >30

Course

episodic

Body systems

hepatic, neurological, dermatologic

Sex differences

AIP: F:M ~5:1 for symptomatic attacks; PCT: M:F ~2:1

Racial and ethnic differences

Founder mutations in specific populations (Swedish, South African)

What this page does not establish

These figures describe populations, not individuals, and none of them is a diagnosis or a treatment recommendation. Prevalence estimates are approximate and reflect published ranges. Disparity figures are reported patterns, not causes.

Taxonomy last reviewed 2026-05-19. Each figure on the interactive page carries its own source and retrieval date, which can be later than this review.

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