Nephrotic Syndrome

Nephrotic Syndrome is indexed under Renal & Urologic, Glomerular Disease. Also known as minimal change disease, focal segmental glomerulosclerosis, FSGS, membranous nephropathy.

US prevalence

~3 per 100,000 children; FSGS increasingly common cause in adults Source: NIDDK; ASN. Cites federal and non-federal sources, and the record does not say which one gave this figure. Label: REPORTED.

ICD-10-CM codes

N04, N04.9

Typical onset

Minimal change: childhood; FSGS: 20-50; membranous: >40

Course

managed

Body systems

renal

Sex differences

Varies by subtype; FSGS M:F ~1.5:1

Racial and ethnic differences

FSGS: much higher in Black Americans (APOL1 gene variants)

What this page does not establish

These figures describe populations, not individuals, and none of them is a diagnosis or a treatment recommendation. Prevalence estimates are approximate and reflect published ranges. Disparity figures are reported patterns, not causes.

Taxonomy last reviewed 2026-05-19. Each figure on the interactive page carries its own source and retrieval date, which can be later than this review.

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