Mucopolysaccharidoses

Mucopolysaccharidoses is indexed under Rare / Orphan Chronic, Lysosomal Storage Disorders. Also known as MPS, Hunter syndrome, Hurler syndrome, Morquio syndrome.

US prevalence

All types combined: ~1 in 25,000; individual types much rarer Source: NIH NINDS; National MPS Society. Cites federal and non-federal sources, and the record does not say which one gave this figure. Label: REPORTED.

ICD-10-CM codes

E76.0, E76.1, E76.2

Typical onset

Infancy/early childhood for severe forms

Course

progressive

Body systems

musculoskeletal, neurological, cardiovascular, respiratory

Sex differences

MPS II (Hunter): X-linked, males only; others equal

Racial and ethnic differences

Pan-ethnic

What this page does not establish

These figures describe populations, not individuals, and none of them is a diagnosis or a treatment recommendation. Prevalence estimates are approximate and reflect published ranges. Disparity figures are reported patterns, not causes.

Taxonomy last reviewed 2026-05-19. Each figure on the interactive page carries its own source and retrieval date, which can be later than this review.

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