Monoclonal Gammopathy of Undetermined Significance

Monoclonal Gammopathy of Undetermined Significance is indexed under Oncologic-Adjacent Chronic, Plasma Cell Disorders. Also known as MGUS.

US prevalence

~3% of adults >50; ~5% >70 Source: ASH. This figure comes from a professional society, registry, or study rather than a federal source. Label: REPORTED.

ICD-10-CM codes

D47.2

Typical onset

Increases with age; median detection ~70

Course

managed

Body systems

hematologic

Sex differences

M:F ~1.5:1

Racial and ethnic differences

2-3x more common in Black Americans

What this page does not establish

These figures describe populations, not individuals, and none of them is a diagnosis or a treatment recommendation. Prevalence estimates are approximate and reflect published ranges. Disparity figures are reported patterns, not causes.

Taxonomy last reviewed 2026-05-19. Each figure on the interactive page carries its own source and retrieval date, which can be later than this review.

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