Metabolic Syndrome

Metabolic Syndrome is indexed under Metabolic & Endocrine, Metabolic. Also known as syndrome X, insulin resistance syndrome, MetS.

US prevalence

38.5% of U.S. adults in NHANES 2021-2023 (95% CI 35.5-41.6%) Source: Trends and Prevalence of the Metabolic Syndrome Among US Adults — NHANES 2013-2023. This figure comes from a professional society, registry, or study rather than a federal source. Label: REPORTED.

ICD-10-CM codes

E88.81

Typical onset

Increases with age; prevalence >50% in those >60

Course

managed

Body systems

endocrine, cardiovascular

Sex differences

Roughly equal overall; women catch up post-menopause

Racial and ethnic differences

Higher in Hispanic Americans

What this page does not establish

These figures describe populations, not individuals, and none of them is a diagnosis or a treatment recommendation. Prevalence estimates are approximate and reflect published ranges. Disparity figures are reported patterns, not causes.

Taxonomy last reviewed 2026-05-19. Each figure on the interactive page carries its own source and retrieval date, which can be later than this review.

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