Hereditary Spherocytosis
Hereditary Spherocytosis is indexed under Rare / Orphan Chronic, Red Cell Membrane Disorders. Also known as HS.
- US prevalence
- ~1 in 2,000 people of Northern European ancestry; prevalence in other ancestry groups is unknown and a U.S.-wide count should not be inferred Source: NIH MedlinePlus Genetics — Hereditary spherocytosis. This figure comes from a professional society, registry, or study rather than a federal source. Label: REPORTED.
- ICD-10-CM codes
- D58.0
- Typical onset
- Childhood; variable severity
- Course
- lifelong
- Body systems
- hematologic
- Sex differences
- Equal (autosomal dominant usually)
- Racial and ethnic differences
- Most common in Northern European; occurs worldwide
What this page does not establish
These figures describe populations, not individuals, and none of them is a diagnosis or a treatment recommendation. Prevalence estimates are approximate and reflect published ranges. Disparity figures are reported patterns, not causes.
Taxonomy last reviewed 2026-05-19. Each figure on the interactive page carries its own source and retrieval date, which can be later than this review.
Browse all indexed conditions · Source registry · Methodology · Known limitations