Hereditary Hemorrhagic Telangiectasia

Hereditary Hemorrhagic Telangiectasia is indexed under Rare / Orphan Chronic, Vascular Malformation. Also known as HHT, Osler-Weber-Rendu syndrome.

US prevalence

Estimated worldwide frequency ~1 in 5,000-10,000 people; true frequency is difficult to determine because disease severity varies Source: NIH MedlinePlus Genetics — Hereditary hemorrhagic telangiectasia. This figure comes from a professional society, registry, or study rather than a federal source. Label: REPORTED.

ICD-10-CM codes

I78.0

Typical onset

Nosebleeds in childhood; AVMs diagnosed 20s-40s

Course

lifelong

Body systems

vascular, pulmonary, hepatic, neurological

Sex differences

Equal (autosomal dominant)

Racial and ethnic differences

Pan-ethnic; Dutch Antilles, Curaçao have higher prevalence

What this page does not establish

These figures describe populations, not individuals, and none of them is a diagnosis or a treatment recommendation. Prevalence estimates are approximate and reflect published ranges. Disparity figures are reported patterns, not causes.

Taxonomy last reviewed 2026-05-19. Each figure on the interactive page carries its own source and retrieval date, which can be later than this review.

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