Gaucher Disease

Gaucher Disease is indexed under Rare / Orphan Chronic, Lysosomal Storage Disorders. Also known as GD, glucocerebrosidase deficiency.

US prevalence

~6,000 (type 1 most common); ~1 in 40,000 general; ~1 in 450 Ashkenazi Jewish Source: National Gaucher Foundation; GeneReviews. This figure comes from a professional society, registry, or study rather than a federal source. Label: REPORTED.

ICD-10-CM codes

E75.22

Typical onset

Type 1: any age; Type 2: infancy; Type 3: childhood

Course

lifelong

Body systems

hematologic, hepatic, musculoskeletal

Sex differences

Equal (autosomal recessive)

Racial and ethnic differences

Much more common in Ashkenazi Jewish descent

What this page does not establish

These figures describe populations, not individuals, and none of them is a diagnosis or a treatment recommendation. Prevalence estimates are approximate and reflect published ranges. Disparity figures are reported patterns, not causes.

Taxonomy last reviewed 2026-05-19. Each figure on the interactive page carries its own source and retrieval date, which can be later than this review.

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