Familial Hypercholesterolemia

Familial Hypercholesterolemia is indexed under Cardiovascular, Genetic Lipid Disorders. Also known as FH, heterozygous FH, homozygous FH.

US prevalence

~1 million U.S. adults with confirmed or probable familial hypercholesterolemia; global prevalence estimate about 1 in 311 Source: CDC — Risk Factors for High Cholesterol; CDC Familial Hypercholesterolemia. Federal source. Label: VERIFIED.

ICD-10-CM codes

E78.01

Typical onset

Lifelong; premature CVD events in 30s-50s if untreated

Course

lifelong

Body systems

cardiovascular

Sex differences

Equal genetic prevalence; men have earlier CVD events

Racial and ethnic differences

Founder effects in certain populations (e.g., Afrikaner, French Canadian, Lebanese)

What this page does not establish

These figures describe populations, not individuals, and none of them is a diagnosis or a treatment recommendation. Prevalence estimates are approximate and reflect published ranges. Disparity figures are reported patterns, not causes.

Taxonomy last reviewed 2026-05-19. Each figure on the interactive page carries its own source and retrieval date, which can be later than this review.

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