Chronic Pain Syndrome

Chronic Pain Syndrome is indexed under Cross-Cutting, Pain. Also known as chronic widespread pain, central sensitization syndrome.

US prevalence

~50 million with chronic pain; ~20 million with high-impact chronic pain Source: CDC NHIS 2019; NIH. Federal source. Label: VERIFIED.

ICD-10-CM codes

G89.29, G89.4

Typical onset

Any age; increases with age

Course

managed

Body systems

neurological, musculoskeletal

Sex differences

More common in women

Racial and ethnic differences

Disparities in treatment; Black patients receive less pain management

What this page does not establish

These figures describe populations, not individuals, and none of them is a diagnosis or a treatment recommendation. Prevalence estimates are approximate and reflect published ranges. Disparity figures are reported patterns, not causes.

Taxonomy last reviewed 2026-05-19. Each figure on the interactive page carries its own source and retrieval date, which can be later than this review.

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