Autoimmune Polyglandular Syndromes
Autoimmune Polyglandular Syndromes is indexed under Autoimmune & Inflammatory, Polyendocrine Autoimmune. Also known as APS type 1, APS type 2, Schmidt syndrome.
- US prevalence
- APS-1: ~1 in 100,000; APS-2: ~1 in 20,000 Source: Endocrine Society; NIH. Cites federal and non-federal sources, and the record does not say which one gave this figure. Label: REPORTED.
- ICD-10-CM codes
- E31.0
- Typical onset
- APS-1: childhood; APS-2: 30-40 years
- Course
- lifelong
- Body systems
- endocrine, dermatologic
- Sex differences
- APS-2 F:M ~3:1; APS-1 equal
- Racial and ethnic differences
- APS-1 higher in Finnish, Sardinian, Iranian Jewish populations
What this page does not establish
These figures describe populations, not individuals, and none of them is a diagnosis or a treatment recommendation. Prevalence estimates are approximate and reflect published ranges. Disparity figures are reported patterns, not causes.
Taxonomy last reviewed 2026-05-19. Each figure on the interactive page carries its own source and retrieval date, which can be later than this review.
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