Adrenal Insufficiency

Adrenal Insufficiency is indexed under Metabolic & Endocrine, Adrenal Disorders. Also known as Addison disease, primary adrenal insufficiency, secondary adrenal insufficiency.

US prevalence

Primary (Addison): ~100-140 per million; secondary more common Source: Endocrine Society; NIH NIDDK. Cites federal and non-federal sources, and the record does not say which one gave this figure. Label: REPORTED.

ICD-10-CM codes

E27.1, E27.4, E27.40

Typical onset

Addison: 30-50 years; secondary at any age

Course

lifelong

Body systems

endocrine

Sex differences

Addison: F:M ~2:1

Racial and ethnic differences

Limited population-level data

What this page does not establish

These figures describe populations, not individuals, and none of them is a diagnosis or a treatment recommendation. Prevalence estimates are approximate and reflect published ranges. Disparity figures are reported patterns, not causes.

Taxonomy last reviewed 2026-05-19. Each figure on the interactive page carries its own source and retrieval date, which can be later than this review.

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